Study shows potential of TAp63 as new therapeutic target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. Clinical outcomes of patients with active RA may be improved by using anti-rheumatic drugs, such as methotrexate (MTX). Many patients rely on MTX to limit the destructive joint damage and functional disability typical of RA. Although the drug is a folic acid antagonist, its … Read more

First tips to optimize the use of PROMs in young people with inflammatory arthritis

PROMs aim to gather information about the impact of a disease on key areas of a person’s life, such as quality of life, ability to perform daily activities, and social or sexual health. This information is useful in addition to disease activity scales and clinical measures to provide a good picture of a person’s overall … Read more

Standardized PedMSUS courses to help assess children with arthritis

Pediatric Musculoskeletal Ultrasound (PedMSUS) has great potential in the assessment of children with arthritis, and since 2012 several PedMSUS courses have been endorsed by EULAR – the European Alliance of Rheumatology Associations. But despite this, there has been no agreed pedagogical procedure for the course, content and format of these courses. This is critical, as … Read more

Unique gut bacteria may be responsible for triggering rheumatoid arthritis in those at risk

Researchers at the University of Colorado School of Medicine have found that a unique bacteria found in the gut may be responsible for triggering rheumatoid arthritis (RA) in people already at risk for the autoimmune disease . Kristine Kuhn, MD, PhD, associate professor of rheumatology, led a team of researchers from the Division of Rheumatology … Read more