Study sheds light on global disparities in liver disease death rates

New research sheds light on global disparities in death rates from advanced liver disease, also known as cirrhosis. The study, published Monday in Lancet Gastroenterology and hepatologyfound that the risk of death for hospitalized patients with cirrhosis was more than twice as high in low- and lower-middle-income countries compared to high-income countries, mainly due to … Read more

Novel gene-editing strategy harnesses unusual protective ability to eliminate HIV-1 infection

The genetic alterations that give rise to a rare and deadly disease known as MOGS-CDG paradoxically also protect cells against infection by viruses. Now, scientists at Temple University’s Lewis Katz School of Medicine have harnessed this unusual protective ability in a novel gene-editing strategy aimed at eliminating HIV-1 infection without adverse effects on mortality. cellular. … Read more

Researchers find that SARS-CoV-2 directly infects hepatocytes that cause hyperglycemia

In a recent study published in PNASresearchers conducted a retrospective cohort study among patients hospitalized with suspected coronavirus disease 2019 (COVID-19) between March and August 2020 in Brazil to determine whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused hyperglycemia. However, the final cohort of the study only included patients whose reverse transcription-polymerase chain reaction … Read more

Study determines diagnostic utility of measuring liver stiffness

Even after recovery from chronic hepatitis C, portal hypertension remains the main factor behind the development of complications in advanced liver disease. In cooperation with Spanish researchers, a research team led by Georg Semmler and Mattias Mandorfer from the Division of Gastroenterology and Hepatology of the Department of Medicine III at MedUni Vienna showed that … Read more

Have COVID-19 mitigation measures in the UK had an impact on the transmission of other infectious diseases?

In a recent study published on medRxiv* preprint server, researchers explored the impact of non-pharmaceutical preventive measures associated with the coronavirus disease 2019 (COVID-19) pandemic on the transmission of 22 infectious diseases in England. Study: Impact of the COVID-19 pandemic on the circulation of other pathogens in England. Image Credit: Rost9/Shutterstock Background Efforts to contain … Read more