Comprehensive nationwide mapping of high-mortality SARS-CoV-2 outbreaks in nursing homes

In a recent study published in the Nature Aging Journal, researchers analyzed data from three SARS-CoV-2 outbreaks in nursing homes in Belgium with high case fatality rates (CFR, 209 to 35%) to identify the risk factors and determine the genetic signature of fatal disease post-coronavirus 2019 (COVID-19) following vaccination. Study: Immunovirological and environmental screening reveals … Read more

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

In a recent study published on medRxiv* preprint server, researchers assessed concurrent colonization of fungi in the nasopharynx of patients with severe coronavirus disease 2019 (COVID-19). They explored the pathways of antifungal immunity by analyzing data from their previous study including patients with acute SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infections. Study: Severe COVID-19 … Read more

Research suggests ORF6 is a major innate immune antagonist of SARS-CoV-2

In a recent study published on bioRxiv* server, researchers in the United States have demonstrated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame protein 6 (ORF6) contributes to viral pathogenesis and modulates immune responses of the virus. ‘host. Study: Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral … Read more